Girlfriends is a contemporary story of Linda, Sue and Gail as they struggle with the responsibilities that come with being a modern woman of a certain age. After the dramatic and sudden death of Linda's husband Micky, childhood friends Linda, Sue and Gail find themselves back together again. Each has their own problems to face; from a looming divorce from the husband she still loves and the loss of a high-powered job through age discrimination, to juggling the endless responsibilities of their grandchildren and aging mothers.